Pachydermoperiostosis Authors : Doctor M . Auger and Professor

Thanatophoric dysplasia Authors: Professor Elio Liboi1 and Doctor

Primary Pachydermoperiostosis and report of two cases in a family

Pachydermoperiostosis (PDP) is a rare hereditary disease characterized by folded coarse skin, hyperostosis, clubbing of fingers and abnormalities in other organs such as gastrointestinal tract. Because of safety parents guides us to familial incidence and penetration of gene in 50% of cases. Diagnosis is based on clinical and radiological findings. Males are more susceptible than females to thi...

Heparin-Induced Thrombocytopenia Authors: Professor Andreas Greinacher2 and Doctor

Best disease Authors : Doctor Dorothea Besch 1 and Professor Eberhart Zrenner Creation

[Pachydermoperiostosis (idiopathic hypertrophic osteoarthropathy)].

Introduction Pachydermoperiostosis is a syndrome characterized by finger clubbing, periosteal new bone formation especially over the distal ends of long bones, and coarsening of the facial features, with thickening, furrowing and oiliness of the skin of the face and forehead. The first reported cases were the Hagner brothers, who had typical features of this syndrome. They were first described ...